Intravenous Vitamin Infusion Therapy (IV Therapy)

Which Vitamins are important for Fertility?

 

IV Nutrient therapy in Ottawa, ON Canada is used for the treatment of many different conditions. It can also be utilized to help support the treatment of female and male infertility. Intravenous vitamin infusions are an innovative method to deliver key minerals and nutrients vital in improving male fertility and sperm health. It can also be used to help protect eggs from damage by delivering high concentration antioxidants and vitamins to support egg quality. 

The most vital ingredient that can be delivered through IV therapy is Glutathione. Glutathione is the main antioxidant compound in the body and has a vital role in protecting sperm cells from damage. It has been shown to help support healthy sperm motility and normal sperm morphology. Glutathione and Vitamin C are two of the main antioxidant compounds which concentrate heavily in the seminal fluid to protect sperm cells from the reactive oxygen species (ROS) they are exposed to. Vitamin C and Glutathione both can be provided in concentrations much higher through an intravenous nutrient infusion than possible with just an oral pill. 

Glutathione is also very important for female infertility and egg quality. Higher glutathione concentrations have been associated with an increased number of embryos which make it to day 5 Blastocyst stage (high quality embryos) during IVF, and lower glutathione levels in the ovary have been associated with a reduced number of follicles making it to the day 5 blastocyst stage. As an antioxidant it supports quality and reduces oxidative stress from harming egg quality.

Additional ingredients that can be added to support fertility for both Men and Women are Carnitine, Arginine, Selenium and Vitamin C. Carnitine helps to improve sperm motility, increase concentration and it also improves egg quality. Arginine helps to improve blood flow to the reproductive organs. The arginine helps to support a healthy uterine lining and can improve thickness of the lining for Women struggling with a thin uterine lining. 

Vitamin C has a crucial role as an antioxidant to support fertility, it also reduces oxidative stress and damage to the eggs and sperm cells. It may help to support optimal progesterone levels, help reduce stress, improve energy, and support the immune system.

Selenium has a crucial role in supporting thyroid function and may help to reduce complications during pregnancy. In particular, it may help to reduce the risk of postpartum hypothyroidism.

For more information see IV Therapy Ottawa

References:

  1. Irvine, D. (1996). Glutathione as a treatment for male infertility. Reviews of Reproduction, 1(1), 6–12.

  2. Mills, J., & Yao, D. (2016). Male infertility: lifestyle factors and holistic, complementary, and alternative therapies. Asian Journal of Andrology, 18(3), 410.

  3. Mora-Esteves, C., & Shin, D. (2013). Nutrient Supplementation: Improving Male Fertility Fourfold. Seminars in Reproductive Medicine, 31(04), 293–300.

  4. Ozawa, M., Nagai, T., Fahrudin, M., Karja, N. W. K., Kaneko, H., Noguchi, J., Kikuchi, K. (2006). Addition of glutathione or thioredoxin to culture medium reduces intracellular redox status of porcine IVM/IVF embryos, resulting in improved development to the blastocyst stage. Molecular Reproduction and Development, 73(8), 998– 1007.

  5. Hidaka, T., Fukumoto, Y., Yamamoto, S., Ogata, Y., & Horiuchi, T. (2018). Variations in bovine embryo production between individual donors for OPU-IVF are closely related to glutathione concentrations in oocytes during in vitro maturation. Theriogenology, 113, 176–182.

  6. Nishihara, T., Matsumoto, K., Hosoi, Y., & Morimoto, Y. (2018). Evaluation of antioxidant status and oxidative stress markers in follicular fluid for human in vitro fertilization outcome. Reproductive Medicine and Biology, 17(4), 481–486.

  7. Majzoub, A., & Agarwal, A. (2018). Systematic review of antioxidant types and doses in male infertility: Benefits on semen parameters, advanced sperm function, assisted reproduction and live-birth rate. Arab Journal of Urology, 16(1), 113–124.

  8. Smits, R. M., Mackenzie-Proctor, R., Yazdani, A., Stankiewicz, M. T., Jordan, V., & Showell, M. G. (2019). Antioxidants for male subfertility. Cochrane Database of Systematic Reviews.

  9. Henmi H, Endo T, Kitajima Y, et al. Effects of ascorbic acid supplementation on serum progesterone levels in patients with luteal phase defect. Fertil Steril 2003;80:459-61.

  10. Igarashi M. Augmentative effect of ascorbic acid upon induction of human ovulation in clomiphene-ineffective anovulatory women. Int J Fertil 1977;22:168-73. 

  11. Showell, M. G., Mackenzie-Proctor, R., Jordan, V., & Hart, R. J. (2017). Antioxidants for female subfertility. Cochrane Database of Systematic Reviews.

  12. Agarwal, A., Sengupta, P., & Durairajanayagam, D. (2018). Role of L-carnitine in female infertility. Reproductive Biology and Endocrinology, 16(1).

  13. Battaglia, C., Salvatori, M., Maxia, N., Petraglia, F., Facchinetti, F., and Volpe, A. Adjuvant L-arginine treatment for in-vitro fertilization in poor responder patients. Hum.Reprod. 1999;14(7):1690-1697.

  14. Appleton, J. (2002). Arginine: Clinical Potential of a Semi-Essential Amino Acid. Alternative Medicine Review, 7(6), 512–522.

Sign up for our Free Fertility Newsletter

©2019 by Infertility & Reproductive Care