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  • Writer's pictureDr. H. Singh, ND

One Infection that Reduces Important Egg Reserve Marker (Anti-Mullerian Hormone Levels)

The intricate fertility journey can sometimes be affected by unexpected challenges. The global COVID-19 pandemic has added another layer of complexity, impacting various aspects of our lives. For couples dealing with infertility, recent studies have shed light on a concerning connection between COVID-19 infection and anti-mullerian hormone (AMH) levels—an essential marker for ovarian reserve.

A meta-analysis of eight studies has revealed that COVID-19 infection significantly reduces AMH levels in biological women. This hormone, which plays a crucial role in estimating ovarian reserve, has become a focus of concern for couples planning for parenthood. Understanding the implications of this connection is vital in navigating the already challenging journey of infertility.

The Impact on Ovarian Reserve:

Anti-mullerian hormone is a key player in assessing ovarian reserve. A decrease in AMH levels can indicate a reduction in the approximate quantity/reserve of an individual's eggs. Newer research has also found a connection linking anti-mullerian hormone levels with the likelihood of obtaining genetically balanced (euploid) embryos during fertility treatments. For couples undergoing fertility treatments, this revelation underscores the importance of staying informed and taking proactive measures.

A meta-analysis, focused on COVID-19 vaccination, did not demonstrate a significant change in AMH levels. This is a crucial piece of information for couples striving to protect their fertility while prioritizing overall health and it should be discussed with your fertility doctor if planning for assisted reproductive treatments, such as, IUI or IVF.

AMH Levels and Euploid Embryos:

In 2023, a comprehensive study revealed a strong correlation between AMH levels and the chances of obtaining euploid embryos—those with a total of 46 chromosomes per cell. Even among patients of similar age groups with the same number of embryos sent for genetic testing from their IVF, higher AMH levels were associated with an increased likelihood of obtaining euploid embryos.

Moving Forward:

As we continue to navigate the ever-evolving landscape of the COVID-19 pandemic, it is essential for couples dealing with infertility to stay informed and work closely with their healthcare providers. Regular check-ups, open communication, and considering protective variables to help prevent infection are crucial steps toward protecting both general health and fertility.


The link between COVID-19 infection and decreased AMH levels adds a new layer of complexity to the fertility journey. These findings emphasize the importance of informed decision-making to help prepare for fertility treatments. As couples face these challenges, staying connected, seeking support, and maintaining a proactive approach can empower them on their fertility journey. And with the right support, every step forward is a step closer to growing your family.

This article is being shared as educational content and is in no way a replacement for medical advice or medical care, it is advised that anyone concerned about their Health should speak with their Naturopathic Doctor. Please discuss with your healthcare provider and only make changes to your medications regimen if recommended by your doctor and under their guidance and supervision.

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